Clinical Microbiology Newsletter
Volume 30, Issue 11 , Pages 79-85 , 1 June 2008

Newer β-Lactamases: Clinical and Laboratory Implications, Part II*

  • Ellen Smith Moland, B.S.M.T.

      Affiliations

    • Corresponding Author InformationMailing Address: Ellen Smith Moland, B.S.M.T., Center for Research in Antiinfectives and Biotechnology, Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, Nebraska 68178. Tel.: 402-280-2921. Fax: 402-280-1875
    • ,
  • Soo-Young Kim, M.D.
    • ,
  • Seong Geun Hong, M.D.
    • ,
  • Kenneth S. Thomson, Ph.D.

References 

  1. Papanicolaou GA , Medeiros AA , Jacoby GA . Novel plasmid-mediated beta-lactamase (MIR-1) conferring resistance to oxyimino- and alpha-methoxy beta-lactams in clinical isolates of Klebsiella pneumoniae . Antimicrob. Agents Chemother. . 1990;34:2200–2209
  2. Bauernfeind A , Chong Y , Schweighart S . Extended broad-spectrum ß-lactamase in Klebsiella pneumoniae including resistance to cephamycins . Infection . 1989;17:316–321
  3. Pai H , et al.   Epidemiology and clinical features of bloodstream infections caused by AmpC-type-beta-lactamase-producing Klebsiella pneumoniae . Antimicrob. Agents Chemother. . 2004;48:3720–3728
  4. Moland ES , et al.   Prevalence of newer β-lactamases in gram-negative clinical isolates collected in the United States from 2001 to 2002 . J. Clin. Microbiol. . 2006;44:3318–3324
  5. Yagi T , et al.   Practical methods using boronic acid compounds for identification of class C {beta}-lactamase-producing Klebsiella pneumoniae and Escherichia coli . J. Clin. Microbiol. . 2005;43:2551–2558
  6. Coudron PE . Inhibitor-based methods for detection of plasmid-mediated AmpC beta-lactamases in Klebsiella spp., Escherichia coli, and Proteus mirabilis . J. Clin. Microbiol. . 2005;43:4163–4167
  7. Jacoby GA , Walsh KE , Walker VJ . Identification of extended-spectrum, AmpC, and carbapenem- hydrolyzing beta-lactamases in Escherichia coli and Klebsiella pneumoniae by disk tests . J. Clin. Microbiol. . 2006;44:1971–1976
  8. Sanders CC , Sanders WE . Emergence of resistance to cefamandole: possible role of cefoxitin-inducible beta-lactamases . Antimicrob. Agents Chemother. . 1979;15:792–797
  9. Queenan AM , Bush K . Carbapenemases: the versatile beta-lactamases . Clin. Microbiol. Rev. . 2007;20:440–458
  10. Livermore DM . Acquired carbapenemases . J. Antimicrob. Chemother. . 1997;39:673–676
  11. Walther-Rasmussen J , Hoiby N . Class A carbapenemases . J. Antimicrob. Chemother. . 2007;60:470–482
  12. Yigit H , et al.   Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem- resistant strain of Klebsiella pneumoniae . Antimicrob. Agents Chemother. . 2001;45:1151–1161
  13. Miriagou V , et al.   Imipenem resistance in a Salmonella clinical strain due to plasmid-mediated class A carbapenemase KPC-2 . Antimicrob. Agents Chemother. . 2003;47:1297–1300
  14. Pottumarthy S , et al.   NmcA carbapenem-hydrolyzing enzyme in Enterobacter cloacae in North America . Emerg. Infect. Dis. . 2003;9:999–1002
  15. Hossain A , et al.   Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp . Antimicrob. Agents Chemother. . 2004;48:4438–4440
  16. Bratu S , et al.   Carbapenemase-producing Klebsiella pneumoniae in Brooklyn, NY: molecular epidemiology and in vitro activity of polymyxin B and other agents . J. Antimicrob. Chemother. . 2005;56:128–132
  17. Bradford PA , et al.   Emergence of carbapenem-resistant Klebsiella species possessing the class A carbapenem-hydrolyzing KPC-2 and inhibitor-resistant TEM-30 beta-lactamases in New York City . Clin. Infect. Dis. . 2004;39:55–60
  18. Woodford N , et al.   Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing class A beta-lactamase, KPC-3, in a New York Medical Center . Antimicrob. Agents Chemother. . 2004;48:4793–4799
  19. Lomaestro BM , et al.   The spread of Klebsiella pneumoniae carbapenemase-producing K. pneumoniae to upstate New York . Clin. Infect. Dis. . 2006;43:e26–e28
  20. Walther-Rasmussen J , Hoiby N . OXA-type carbapenemases . J. Antimicrob. Chemother. . 2006;57:373–383
  21. Poirel L , Nordmann P . Acquired carbapenem-hydrolyzing beta-lactamases and their genetic support . Curr. Pharm. Biotechnol. . 2002;3:117–127
  22. Heritier C , et al.   Contribution of acquired carbapenem-hydrolyzing oxacillinases to carbapenem resistance in Acinetobacter baumannii . Antimicrob. Agents Chemother. . 2005;49:3198–3202
  23. Donald HM , et al.   Sequence analysis of ARI-1, a novel OXA beta-lactamase, responsible for imipenem resistance in Acinetobacter baumannii 6B92 . Antimicrob. Agents Chemother. . 2000;44:196–199
  24. Anderson KF , et al.   Evaluation of methods to identify the Klebsiella pneumoniae carbapenemase in Enterobacteriaceae . J. Clin. Microbiol. . 2007;45:2723–2725
  25. Hirakata Y , et al.   Rapid detection and evaluation of clinical characteristics of emerging multiple-drug-resistant gram-negative rods carrying the metallo-beta-lactamase gene blaIMP . Antimicrob. Agents Chemother. . 1998;42:2006–2011
  26. Lee K , et al.   Modified Hodge and EDTA-disk synergy tests to screen metallo-beta-lactamase-producing strains of Pseudomonas and Acinetobacter species . Clin. Microbiol. Infect. . 2001;7:88–91
  27. Walsh TR , et al.   Evaluation of a new Etest for detecting metallo-beta-lactamases in routine clinical testing . J. Clin. Microbiol. . 2002;40:2755–2759
  28. Migliavacca R , et al.   Simple microdilution test for detection of metallo-beta-lactamase production in Pseudomonas aeruginosa . J. Clin. Microbiol. . 2002;40:4388–4390
  29. Arakawa Y , et al.   Convenient test for screening metallo-beta-lactamase-producing gram-negative bacteria by using thiol compounds . J. Clin. Microbiol. . 2000;38:40–43
  30. Yong D , et al.   Imipenem-EDTA disk method for differentiation of metallo-beta-lactamase-producing clinical isolates of Pseudomonas spp. and Acinetobacter spp . J. Clin. Microbiol. . 2002;40:3798–3801
  31. Livermore DM , Warner M , Mushtaq S . Evaluation of the chromogenic Cica-(beta)-test for detecting extended-spectrum, AmpC and metallo-(beta)-lactamases . J. Antimicrob. Chemother. . 2007;60:1375–1379
  32. Kim SY , et al.   Convenient test using a combination of chelating agents for detection of metallo-(beta)-lactamases in the clinical laboratory . J. Clin. Microbiol. . 2007;45:2798–2801
  33. Medeiros AA . Evolution and dissemination of β-lactamases accelerated by generations of β-lactam antibiotics . Clin. Infect. Dis. . 1997;24(Suppl. 1):S19–S45

PII: S0196-4399(08)00025-1

doi: 10.1016/j.clinmicnews.2008.05.001

Clinical Microbiology Newsletter
Volume 30, Issue 11 , Pages 79-85 , 1 June 2008

Article Tools

* Image Usage & Resolution