Clinical Microbiology Newsletter
Volume 30, Issue 24 , Pages 183-188, 15 December 2008

GeneXpert Testing: Applications for Clinical Microbiology, Part II

  • Elizabeth M. Marlowe, Ph.D., D(ABMM)

      Affiliations

    • Southern California Permanente Medical Group, Regional Reference Laboratories, North Hollywood, California
    • Corresponding Author InformationMailing Address: Elizabeth M. Marlowe, Ph.D., D(ABMM), Southern California Permanente Medical Group, Regional Reference Laboratories, North Hollywood, CA 91605. Tel.: 818-503-7067. Fax: 818-503-6713
    • ,
  • Donna M. Wolk, Ph.D., D(ABMM)

      Affiliations

    • Department of Pathology, University of Arizona, College of Medicine, BIO5 Institute, Tucson, Arizona

Abstract 

The impact of rapid polymerase chain reaction (PCR) technology on infectious-disease testing is continuing to evolve outside the realm of a centralized laboratory. The GeneXpert Dx system is the first unit dose, near-point-of-care, molecular device commercially available. Part I of this two-part article addressed the use of the GeneXpert system for the detection of group B Streptococcus, enterovirus, and methicillin-resistant and methicillin-susceptible Staphylococcus aureus in various clinical specimens. Part II of this article will review the advantages and disadvantages of conventional culture methods and alternative molecular technologies along with the GeneXpert system, for the detection of these microorganisms in clinical specimens.

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 Editor's Note: Part I of this article was published in the December 1, 2008 issue of CMN (Vol. 30, No. 23).

PII: S0196-4399(08)00059-7

doi:10.1016/j.clinmicnews.2008.11.004

Clinical Microbiology Newsletter
Volume 30, Issue 24 , Pages 183-188, 15 December 2008

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