Clinical Microbiology Newsletter
Volume 31, Issue 4 , Pages 25-30 , 15 February 2009

Microbial Monitoring in the Pharmacy

  • Alice S. Weissfeld, Ph.D., D(ABMM), F(AAM)

      Affiliations

    • Corresponding Author InformationMailing Address: Alice S. Weissfeld, Ph.D., D(ABMM), F(AAM), Microbiology Specialists Incorporated, 8911 Interchange Dr., Houston, TX 77054. Tel.: 713-663-6888. Fax 713-663-7722
    • ,
  • Paula H. Vance, B.A., SM(ASCP), SM(NRM), M(CLSp), CIE

References 

  1. Kastengo ES . USP chapter 〈797〉 and environmental monitoring . Clin. Microbiol. Newsl. . 2008;30:105–108
  2. U.S. Pharmacopeial Convention  . Pharmaceutical compounding: sterile preparations . In: U.S. Pharmacopeia 27 – national formulary 22 . Rockville, MD: U.S. Pharmacopeial Convention; 2004;p. 2461–2477
  3. U.S. Pharmacopeial Convention  . Revision bulletin, December 2007. Chapter 〈797〉 pharmaceutical compounding – sterile preparations . http://www.usp.org/pdf/EN/USPNF/generalchapter797.pdf 2007;
  4. Solomon SL , et al.   An outbreak of Candida parapsilosis bloodstream infection in patients receiving parenteral nutrition . J. Infect. Dis. . 1984;149:98–102
  5. Hughes CF , et al.   Cardioplegia solution: a contamination crisis . J. Thorac. Cardiovasc. Surg. . 1986;91:296–302
  6. Tresoldi AT . Enterobacter cloacae sepsis outbreak in a newborn unit caused by contaminated total parenteral nutrition solution . Am. J. Infect. Contr. . 2000;28:258–261
  7. Centers for Disease Control and Prevention  . Exophiala infection from contaminated injectable steroids prepared by a compounding pharmacy . MMWR Morb. Mortal. Wkly. Rep. . 2002;51:1109–1112
  8. Selenic D , et al.   Enterobacter cloaecae bloodstream infections in pediatric patients traced to a hospital pharmacy . Am. J. Health Syst. Pharm. . 2003;60:1440–1446
  9. Centers for Disease Control and Prevention  . Pseudomonas bloodstream infections associated with a heparin/saline flush – Missouri, New York, Texas, and Michigan. 2004-2005 . MMWR Morb. Mortal. Wkly. Rep. . 2005;54:269–272
  10. Givens R , et al.   Outbreak of Serratia marsescens infection following injections of betamethasone compounded at a community pharmacy . Clin. Infect. Dis. . 2005;43:831–837
  11. Patel R , et al.   Hepatitis C virus infections from a contaminated radio-pharmaceutical used in myocardial perfusion studies . JAMA . 2006;296:2005–2011
  12. Gresham MD , et al.   Multistate outbreak of Pseudomonas fluorescens bloodstream infection after exposure to contaminated heparinized saline flush prepared by a compounding pharmacy . Clin. Infect. Dis. . 2008;47:1372–1379
  13. U.S. Food and Drug Administration  . Guideline on sterile drug products produced by aseptic processing . Rockville, MD: FDA; 2004; http://www.fda.gov/Cder/guidance/5882fnl.pdf
  14. U.S. Pharmacopeial Convention  . Sterility tests . In: U.S. Pharmacopeia 27 – National formulary 22 . Rockville, MD: U.S. Pharmacopeial Convention; 2004;p. 2157–2162
  15. U.S. Pharmacopeial Convention  . Bacterial endotoxins test . In: U.S. Pharmcopeia 27 — National Formulary 22 . Rockville, MD: U.S. Pharmacopeial Convention; 2004;p. 2169–2173

PII: S0196-4399(09)00005-1

doi: 10.1016/j.clinmicnews.2009.01.004

Clinical Microbiology Newsletter
Volume 31, Issue 4 , Pages 25-30 , 15 February 2009

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