Clinical Microbiology Newsletter
Volume 31, Issue 22 , Pages 172-174 , 15 November 2009

Recurrent Skin Abscesses Caused by Panton-Valentine Leukocidin-Producing Methicillin-Susceptible Staphylococcus aureus

  • N. Van Gasse, M.D.

      Affiliations

    • Department of Microbiology, GZA Sint-Augustinus, Wilrijk, Belgium
    • Corresponding Author InformationMailing address: Natasja Van Gasse, M.D., Laboratory of Microbiology, Oosterveldlaan 24, 2610 Wilrijk, Belgium. Tel.: 003232853941. Fax: 003232852948
    • ,
  • A. Jeurissen, M.D., Ph.D.

      Affiliations

    • Department of Microbiology, GZA Sint-Augustinus, Wilrijk, Belgium
    • ,
  • J. Van Schaeren, M.D.

      Affiliations

    • Department of Microbiology, GZA Sint-Augustinus, Wilrijk, Belgium
    • ,
  • J.-P. Ursi, M.D., PhD.

      Affiliations

    • Department of Microbiology, GZA Sint-Augustinus, Wilrijk, Belgium
    • ,
  • P. Borgers, M.D.

      Affiliations

    • Department of Internal Medicine, GZA Sint-Jozef, Mortsel, Belgium

References 

  1. Dinges MM , Orwin PM , Schlievert PM . Exotoxins of Staphylo coccus aureus . Clin. Microbiol. Rev. . 2000;13:16–43
  2. Badoui C , et al.   Panton-Valentine leukocidin is expressed at toxic levels in human skin abscesses . Clin. Microbiol. Infect. . 2008;14:1180–1183
  3. Gorak EJ , Yamada SM , Brown JD . Community-acquired methicillin-resistant Staphylococcus aureus in hospitalized adults and children without known risk factors . Clin. Infect. Dis. . 1999;29:797–800
  4. Kluytmans J , van Belkum A , Verbrugh H . Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks . Clin. Microbiol. Rev. . 1997;10:505–520
  5. Issartel B , et al.   Frequent carriage of Panton-Valentine leukocidin genes by Staphylococcus aureus isolates from surgically drained abscesses . J. Clin. Microbiol. . 2005;43:3203–3207
  6. Graham PL , Lin S , Larson E . A U.S. population-based survey of Staphylococcus aureus colonization . Ann. Intern. Med. . 2006;144:318–325
  7. Supersac G , Prevost G , Piemont Y . Sequencing of leucocidin R from Staphylococcus aureus P83 suggests that staphylococcal leucocidins and gamma-hemolysin are members of a single, two-component family of toxins . Infect. Immun. . 1993;61:580–587
  8. Prévost G , et al.   The new family of leucotoxins from Staphylococcus aureus: structural and biological properties . Zentralbl. Bakteriol. Suppl. . 1994;24:284–293
  9. Yamasaki O , et al.   The association between Staphylococcus aureus strains carrying Panton-Valentine leukocidin genes and the development of deep-seated follicular infection . Clin. Infect. Dis. . 2005;40:381–385
  10. Lina G , et al.   Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia . Clin. Infect. Dis. . 1999;29:1128–1132
  11. Labandeira-Rey M , et al.   Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia . Science . 2007;315:1130–1133
  12. Vandenesch F , et al.   Community-acquired methicillin-resistant Staphylo coccus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence . Emerg. Infect. Dis. . 2003;9:978–984
  13. Melles DC , et al.   Panton-Valentine leukocidin genes in Staphylococcus aureus . Emerg. Infect. Dis. . 2006;12:1174–1175
  14. Severin JA , et al.   Unusually high prevalence of Panton-Valentine leukocidin genes among methicillin-sensitive Staphylococcus aureus strains carried in the Indonesian population . J. Clin. Microbiol. . 2008;46:1989–1995
  15. Ditzen A , Ehricht R , Monecke S . Disseminated cutaneous and pulmonary abscesses in an injecting drug user caused by a Panton-Valentine leucocidin-positive, methicillin-susceptible Staphylococcus aureus strain . Eur. J. Clin. Microbiol. Infect. Dis. . 2008;27:1013–1015
  16. Monecke S , et al.   Microarray-based characterisation of a Panton-Valentine leukocidin-positive community-acquired strain of methicillin-resistant Staphylococcus aureus . Clin. Microbiol. Infect. . 2006;12:718–728
  17. Von Eiff C , et al.   Nasal carriage as a source of Staphylococcus aureus bacteremia . N. Engl. J. Med. . 2001;344:11–16
  18. Wertheim HFL , et al.   Optimaliseren van het antibioticabeleid in Nederland . XII. SWAB-richtlijn voor de behandeling van MRSA-dragerschap. Ned. Tijdschr. Geneeskd. . 2008;152:2667–2671

PII: S0196-4399(09)00049-X

doi: 10.1016/j.clinmicnews.2009.10.003

Clinical Microbiology Newsletter
Volume 31, Issue 22 , Pages 172-174 , 15 November 2009

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