Clinical Microbiology Newsletter
Volume 32, Issue 1 , Pages 1-6 , 1 January 2010

The Best Practices for Screening, Monitoring, and Diagnosis of Cytomegalovirus Disease, Part I

  • Tiziana Lazzarotto, Ph.D.

      Affiliations

    • Corresponding Author InformationMailing address: T. Lazzarotto, Ph.D., U.O. Microbiologia, Policlinico S. Orsola-Malpighi, Via Massarenti n. 9, 40138 Bologna, Italy. Tel.: +39.051.636.3360. Fax: +39.051.307397

References 

  1. Mocarski ES , Shenk T , Pass RF . Cytomegalovirus . In:  Knipe DM ,  Howley PM editor. Fields virology . 5th ed.. Philadelphia, PA: Lippincott Williams and Wilkins; 2007;p. 2701–2772
  2. Landolfo S , et al.   The human cytomegalovirus . Pharmacol. Ther. . 2003;98:269–297
  3. Fishman JA . Infection in solid-organ transplant recipients . N. Engl. J. Med. . 2007;357:2601–2614
  4. Razonable RR , Emery VC . Management of CMV infection and disease in transplant patients . Herpes . 2004;11:77–86
  5. Gerna G , Lilleri D . Monitoring transplant patients for human cytomegalovirus: diagnostic update . Herpes . 2006;4:11–13
  6. Lilleri D , et al.   Multicenter quality control study for human cytomegalovirus DNAemia quantification . New Microbiol. . 2009;32:245–253
  7. Pang XL , et al.   Interlaboratory comparison of cytomegalovirus viral load assays . Am. J. Transplant. . 2009;9:258–268
  8. Caliendo A.M., et al. A commutable cytomegalovirus calibrator is required to improve the agreement of viral load values between laboratories. Clin. Chem. 55:1701–1710.
  9. Razonable RR , et al.   The clinical use of various blood compartments for cytomegalovirus (CMV) DNA quantitation in transplant recipients with CMV disease . Transplantation . 2002;73:968–973
  10. Snydman DR . Counterpoint: prevention of cytomegalovirus (CMV) infection and CMV disease in recipients of solid organ transplant: the case for prophylaxis . Clin. Infect. Dis. . 2005;40:709–712
  11. Singh N . Late-onset cytomegalovirus disease as a significant complication in solid organ transplant recipients receiving antiviral prophylaxis: a call to heed the mounting evidence . Clin. Infect. Dis. . 2005;40:704–708
  12. Gerna G , et al.   Monitoring of human cytomegalovirus-specific CD4 and CD8 T-cell immunity in patients receiving solid organ transplantation . Am. J. Transplant . 2006;6:2356–2364
  13. Chiereghin A., et al. 2009. Monitoring of CMV T-cell immunity in patients receiving small bowel/multivisceral transplantation. OR 43, p. 73. In Abstr. XIth Int. Small Bowel Transplant Sympo., 9–12 September, Bologna, Italy.

 Editor's Note: Part II of this article will be published in the January 15, 2010 issue of CMN (Vol. 32, No. 2).

PII: S0196-4399(09)00059-2

doi: 10.1016/j.clinmicnews.2009.12.001

Clinical Microbiology Newsletter
Volume 32, Issue 1 , Pages 1-6 , 1 January 2010